Is Libersus as effective as Ozempic?
Like Ozempic, Libersus can be an effective type 2 diabetes treatment, but it’s important to note that each is absorbed differently, so different doses can be used.
According to the FDA, a maximum daily dose of 14 milligrams (mg) of Libersus is equivalent to a weekly dose of 0.5 mg of Ozempic. You can switch from one to the other without adjusting the dosage. (Libersus uses a higher amount of semaglutide than Ozempic because only a portion of the semaglutide that goes into the stomach is properly absorbed.)
A real-world data study found that oral semaglutide had “similar efficacy” to injectable semaglutide for blood sugar control.
These results suggest that Rybelsus and Ozempic may be similarly effective for people with type 2 diabetes, but the two drugs are not actually equivalent because Ozempic is available in a more potent dose.
Ozempic is also available in 1 mg and 2 mg doses. When metformin was tested at the highest dose in patients with type 2 diabetes, it lowered A1C by 2.2 percentage points and reduced body weight by just over 15 pounds. Rybelsus cannot match these results, at least at the approved doses. Wegovy is approved for even higher doses: 2.4 mg per week as an injection and 25 mg per day in tablets.
